Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 11/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356401 | 0.93 | CACNA1B (0.62) | CACNA1BMEN1KMT2AHTR2APTPN1 | |
| SCHEMBL7352934 | 0.84 | CACNA1B (0.61) | CACNA1BMEN1KMT2APTPN1JAK2 | |
| SCHEMBL7349970 | 0.84 | CACNA1B (0.63) | CACNA1BMEN1KMT2APTPN1 | |
| SCHEMBL7358077 | 0.84 | CACNA1B (0.64) | CACNA1BMEN1KMT2AJAK2JAK1 | |
| SCHEMBL7043365 | 0.83 | CACNA1B (0.73) | CACNA1BMEN1KMT2AOPRD1 | |
| SCHEMBL7349295 | 0.83 | CACNA1B (0.56) | CACNA1BMEN1KMT2APTPN1JAK2 | |
| SCHEMBL7357575 | 0.82 | CACNA1B (0.47) | CACNA1BMEN1KMT2AOPRD1 | |
| SCHEMBL7043363 | 0.82 | CACNA1B (0.60) | CACNA1BMEN1KMT2ACA1CA2 | |
| SCHEMBL7357264 | 0.81 | CACNA1B (0.47) | CACNA1BMEN1KMT2AHTR2A | |
| SCHEMBL7352294 | 0.79 | CACNA1B (0.46) | CACNA1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | claimed |
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |