Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.63 |
| ▸ | IGF1R | P08069 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2796836 | 0.87 | GAA (0.82) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL10746494 | 0.87 | GAA (0.82) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL11072473 | 0.83 | GAA (0.43) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL6979453 | 0.83 | GAA (0.71) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL1205842 | 0.83 | GAA (0.71) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL3082979 | 0.83 | GAA (0.71) | GAAKMT2AMEN1KDM4EOPRM1 | |
| Hydrochloric Acid SCHEMBL3089754 | 0.81 | GAA (0.69) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL12573567 | 0.81 | GAA (0.69) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL8223804 | 0.81 | GAA (0.69) | GAAKMT2AMEN1KDM4EOPRM1 | |
| SCHEMBL1460306 | 0.81 | GAA (0.69) | GAAKMT2AMEN1KDM4EOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |