Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 5/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15841419 | 1.00 | OR51E2 (0.43) | OR51E2TP53SMN1; SMN2TET2KDM4A | |
| SCHEMBL16600433 | 0.85 | OR51E2 (0.40) | OR51E2TP53SMN1; SMN2TET2KDM4A | |
| SCHEMBL28410668 | 0.84 | OR51E2 (0.43) | OR51E2TP53SMN1; SMN2TET2KDM4A | |
| SCHEMBL3692471 | 0.83 | OR51E2 (0.39) | OR51E2TP53SMN1; SMN2TET2KDM4A | |
| SCHEMBL9356193 | 0.80 | TP53 (0.40) | OR51E2TP53SMN1; SMN2TET2KDM4A | |
| SCHEMBL185354 | 0.78 | — | — | |
| SCHEMBL361589 | 0.78 | — | — | |
| SCHEMBL1336542 | 0.78 | — | — | |
| SCHEMBL28482603 | 0.78 | OR51E2 (0.48) | OR51E2TP53SMN1; SMN2TET2KDM4A | |
| SCHEMBL28172667 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783677-A | FORMING INTERMEDIATES BY TREATING 6-DEOXY-A-L-MANNOPYRANOSYL BROMIDE AND 2,3,4-TRI-O-BENZOATE WITH DIMETHYLSULFOXIDE, A BASE, AND A SOLVENT | PROCTER & GAMBLE PHARMACEUTICALS, INC. | 1998-07-21 | — | — | US | disclosed |
| US-5721217-A | 14-AMINOANDROSTANE COMPOUNDS AS INOTROPIC AGENT TREATING CONGESTIVE HEART FAILURE | THE PROCTER & GAMBLE COMPANY (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0720616-A1 | NOVEL DEOXY AND OXYGEN-SUBSTITUTED SUGAR-CONTAINING 14-AMINOSTEROID COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008558-A1 | NOVEL DEOXY AND OXYGEN-SUBSTITUTED SUGAR-CONTAINING 14-AMINOSTEROID COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1995-03-30 | — | — | WO | disclosed |