SCHEMBL7353035

SCHEMBL7353035

CCN(CC)CCC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3Cl)cc2C)c2ccc(F)cc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AVPR2 P30518 14/20 0.60
AVPR1A P37288 5/20 0.54
ABCB11 O95342 2/20 0.54
HTR1A P08908 2/20 0.54
CHRM1 P11229 2/20 0.54
OPRM1 P35372 2/20 0.54
ADRB2 P07550 1/20 0.54
ADORA3 P0DMS8 1/20 0.54
TBXA2R P21731 1/20 0.54
HTR2C P28335 1/20 0.54
HRH1 P35367 1/20 0.54
GLP1R P43220 1/20 0.54
TMEM97 Q5BJF2 1/20 0.54
FFAR4 Q5NUL3 1/20 0.54
GPR119 Q8TDV5 1/20 0.54
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
OXTR P30559 1/20 0.42
SLC6A4 P31645 1/20 0.42
ADRA1A P35348 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7352066 0.93 AVPR2 (0.69) AVPR2AVPR1AABCB11HTR1ACHRM1
SCHEMBL4687985 0.88 AVPR2 (0.51) AVPR2AVPR1AABCB11HTR1ACHRM1
SCHEMBL7349261 0.88 AVPR2 (0.55) AVPR2AVPR1AABCB11HTR1ACHRM1
SCHEMBL7356031 0.87 AVPR2 (0.54) AVPR2AVPR1AABCB11HTR1ACHRM1
SCHEMBL4686113 0.86 AVPR2 (0.52) AVPR2AVPR1AABCB11HTR1ACHRM1
SCHEMBL7356522 0.85 AVPR2 (0.66) AVPR2AVPR1AABCB11HTR1ACHRM1
SCHEMBL7354159 0.83 AVPR2 (0.57) AVPR2AVPR1AABCB11HTR1ACHRM1
Hydrochloric Acid SCHEMBL4741673 0.80 AVPR2 (0.59) AVPR2AVPR1AABCB11HTR1ACHRM1
Hydrochloric Acid SCHEMBL4685226 0.80 AVPR2 (0.67) AVPR2AVPR1AABCB11HTR1ACHRM1
SCHEMBL7357001 0.80 AVPR2 (0.66) AVPR2AVPR1AABCB11HTR1ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed