Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL7360612 | 1.00 | CA12 (0.52) | CA12CA1CA2CA9ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL7354978 | 1.00 | CA12 (0.52) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL2409552 | 0.98 | CA12 (0.53) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL1666565 | 0.98 | CA12 (0.53) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL200488 | 0.98 | CA12 (0.53) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL20973808 | 0.91 | CA12 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL22370881 | 0.91 | CA12 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL19582680 | 0.91 | CA12 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| Butane SCHEMBL28217400 | 0.88 | CA12 (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| Alcohol SCHEMBL7359179 | 0.88 | CA12 (0.46) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922703-A | USEFUL FOR TREATING CONGESTIVE HEART FAILURE | THE PROCTER & GAMBLE COMPANY (US) | 1999-07-13 | — | — | US | disclosed |
| EP-0720617-B1 | NOVEL URETHANE-CONTAINING AMINOSTEROID COMPOUNDS | PROCTER & GAMBLE (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0720617-A1 | NOVEL URETHANE-CONTAINING AMINOSTEROID COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008559-A1 | NOVEL URETHANE-CONTAINING AMINOSTEROID COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1995-03-30 | — | — | WO | disclosed |