Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 7/20 | 0.70 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.70 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | OXTR | P30559 | 1/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345848 | 0.91 | AVPR1A (0.83) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL7383625 | 0.83 | AVPR2 (0.63) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL7352677 | 0.83 | AVPR1A (0.80) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL7348782 | 0.83 | AVPR1A (0.80) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL7353668 | 0.83 | AVPR1A (0.80) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL7348322 | 0.83 | AVPR1A (0.77) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL7353531 | 0.83 | AVPR1A (0.64) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL7352805 | 0.82 | AVPR1A (0.79) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL7353026 | 0.82 | AVPR1A (0.79) | AVPR1AAVPR2AVPR1BABCB11HTR1A | |
| SCHEMBL7346631 | 0.82 | AVPR1A (0.79) | AVPR1AAVPR2AVPR1BABCB11HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846514-A | Enhancement of the efficacy of nifedipine by deuteration | ISOTECHNIKA, INC. (CA) | 1998-12-08 | — | — | US | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |