Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290055 | 0.95 | EPHX1 (0.41) | HPGDSMN1; SMN2USP2LMNAEPHX1 | |
| SCHEMBL7351742 | 0.88 | DRD4 (0.37) | HPGDSMN1; SMN2USP2LMNATP53 | |
| SCHEMBL19157470 | 0.86 | EPHX1 (0.45) | HPGDSMN1; SMN2USP2LMNAEPHX1 | |
| SCHEMBL15108788 | 0.86 | EPHX1 (0.45) | HPGDSMN1; SMN2USP2LMNAEPHX1 | |
| SCHEMBL2199451 | 0.86 | EPHX1 (0.45) | HPGDSMN1; SMN2USP2LMNAEPHX1 | |
| SCHEMBL16790400 | 0.84 | EPHX1 (0.48) | HPGDSMN1; SMN2USP2LMNAEPHX1 | |
| SCHEMBL7517942 | 0.84 | EPHX1 (0.48) | HPGDSMN1; SMN2USP2LMNAEPHX1 | |
| SCHEMBL18269644 | 0.84 | EPHX1 (0.42) | HPGDSMN1; SMN2USP2LMNAEPHX1 | |
| SCHEMBL2198817 | 0.84 | EPHX1 (0.42) | HPGDSMN1; SMN2USP2LMNAEPHX1 | |
| SCHEMBL7355885 | 0.83 | HPGD (0.36) | HPGDSMN1; SMN2USP2LMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |