Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657753 | 0.98 | CXCR4 (0.52) | CXCR4SIGMAR1POLBSMN1; SMN2GNAO1 | |
| SCHEMBL947587 | 0.92 | CXCR4 (0.50) | CXCR4SIGMAR1POLBSMN1; SMN2HRH3 | |
| SCHEMBL986238 | 0.85 | HRH3 (0.46) | GNAO1GNAI3GNAI1HRH3TSHR | |
| SCHEMBL984275 | 0.85 | HRH3 (0.46) | GNAO1GNAI3GNAI1HRH3TSHR | |
| SCHEMBL999934 | 0.83 | SMN1; SMN2 (0.45) | CXCR4SIGMAR1POLBSMN1; SMN2TSHR | |
| SCHEMBL11726023 | 0.82 | CXCR4 (0.74) | CXCR4SIGMAR1POLBSMN1; SMN2GNAO1 | |
| SCHEMBL21569302 | 0.82 | CXCR4 (0.74) | CXCR4SIGMAR1POLBSMN1; SMN2GNAO1 | |
| SCHEMBL11721752 | 0.82 | CXCR4 (0.74) | CXCR4SIGMAR1POLBSMN1; SMN2GNAO1 | |
| Hydrochloric Acid SCHEMBL8822105 | 0.81 | SMN1; SMN2 (0.43) | CXCR4SIGMAR1POLBSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8822030 | 0.81 | SMN1; SMN2 (0.43) | CXCR4SIGMAR1POLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700306-B2 | characterising a polypeptide by matrix assisted laser desorption ionization (MALDI) mass spectrometry; improving sensitivity, and can increase the number of peptides that are detected from a protein | ELECTROPHORETICS LIMITED (GB) | 2010-04-20 | — | — | US | disclosed |
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |