Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 11/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107659 | 0.88 | USP30 (0.46) | NPC1ALOX15HTTRAB9AF10 | |
| SCHEMBL6107816 | 0.87 | NPC1 (0.49) | NPC1ALOX15HTTRAB9AF10 | |
| SCHEMBL6717550 | 0.82 | F10 (0.45) | NPC1ALOX15HTTRAB9AF10 | |
| SCHEMBL6108150 | 0.82 | F10 (0.51) | NPC1ALOX15HTTRAB9AF10 | |
| SCHEMBL6106400 | 0.81 | F10 (0.46) | NPC1ALOX15HTTRAB9AF10 | |
| SCHEMBL6112192 | 0.81 | NPC1 (0.50) | NPC1ALOX15HTTRAB9AF10 | |
| SCHEMBL6607911 | 0.80 | NPC1 (0.48) | NPC1ALOX15HTTRAB9AF10 | |
| SCHEMBL6107563 | 0.80 | F10 (0.59) | NPC1ALOX15HTTRAB9AF10 | |
| SCHEMBL6109182 | 0.79 | NPC1 (0.51) | NPC1ALOX15HTTRAB9AF10 | |
| SCHEMBL6108386 | 0.79 | F10 (0.49) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |