Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PKLR | P30613 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.33 |
| ▸ | PTPRS | Q13332 | 4/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352457 | 0.95 | F2 (0.45) | F2GAATSHRALDH1A1PKLR | |
| SCHEMBL7356550 | 0.94 | F2 (0.47) | F2GAATSHRALDH1A1MAPT | |
| SCHEMBL7353074 | 0.89 | F2 (0.46) | F2GAATSHRALDH1A1MAPT | |
| SCHEMBL7353216 | 0.88 | F2 (0.58) | F2GAATSHRALDH1A1PTPN1 | |
| SCHEMBL8144538 | 0.83 | F2 (0.66) | F2GAATSHRALDH1A1PKLR | |
| Iodide SCHEMBL7357519 | 0.82 | F2 (0.55) | F2GAATSHRALDH1A1PTPN1 | |
| Iodide SCHEMBL7362204 | 0.81 | F2 (0.56) | F2GAATSHRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7360424 | 0.81 | F2 (0.55) | F2GAATSHRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7352296 | 0.80 | F2 (0.68) | F2TSHRALDH1A1MAPTPTPN1 | |
| Hydrochloric Acid SCHEMBL7381526 | 0.80 | F2 (0.62) | F2ALDH1A1MAPTPTPN1PTPRS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |