Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 11/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348378 | 0.88 | CACNA1B (0.49) | CACNA1BLMNASMN1; SMN2CCR5ALOX5 | |
| SCHEMBL7349161 | 0.88 | CACNA1B (0.51) | CACNA1BLMNASMN1; SMN2CCR5ALDH1A1 | |
| SCHEMBL7349212 | 0.86 | CACNA1B (0.59) | CACNA1BLMNASMN1; SMN2CCR5ALOX5 | |
| SCHEMBL7351424 | 0.86 | CACNA1B (0.59) | CACNA1BLMNASMN1; SMN2ALOX5OPRD1 | |
| SCHEMBL7353923 | 0.86 | CACNA1B (0.55) | CACNA1BLMNASMN1; SMN2CCR5ALOX5 | |
| SCHEMBL7359677 | 0.84 | CACNA1B (0.62) | CACNA1BLMNASMN1; SMN2CCR5ALOX5 | |
| SCHEMBL7354272 | 0.84 | CACNA1B (0.61) | CACNA1BLMNASMN1; SMN2CCR5ALOX5 | |
| SCHEMBL7349288 | 0.83 | CACNA1B (0.51) | CACNA1BLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7359516 | 0.83 | CACNA1B (0.70) | CACNA1BLMNASMN1; SMN2ALOX5OPRD1 | |
| SCHEMBL7354077 | 0.82 | CACNA1B (0.58) | CACNA1BLMNASMN1; SMN2CCR5ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |