SCHEMBL7356746

SCHEMBL7356746

C=C/C=C(\[C]=O)CCCC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.36
CES2 O00748 2/20 0.36
ALDH1A1 P00352 3/20 0.33
TP53 P04637 1/20 0.33
CA1 P00915 1/20 0.32
TSHR P16473 3/20 0.32
FAAH O00519 1/20 0.32
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7356748 1.00 CES1 (0.36) CES1CES2ALDH1A1TP53CA1
SCHEMBL12829801 0.79 CES1 (0.32) CES1CES2ALDH1A1TSHR
SCHEMBL9474926 0.72 TSHR (0.37) CES1CES2ALDH1A1TSHRFAAH
SCHEMBL8511148 0.72 TSHR (0.37) CES1CES2ALDH1A1TSHRFAAH
SCHEMBL1685573 0.70 TSHR (0.38) CES1CES2ALDH1A1TP53CA1
SCHEMBL28363364 0.69
SCHEMBL184574 0.69
SCHEMBL8583365 0.69
SCHEMBL7130944 0.69
SCHEMBL184575 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602209-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-22 EP disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed