Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.48 |
| ▸ | F2 | P00734 | 6/20 | 0.48 |
| ▸ | PLG | P00747 | 4/20 | 0.46 |
| ▸ | PROC | P04070 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277890 | 1.00 | F10 (0.50) | F10PRSS1F2PLGPROC | |
| SCHEMBL7385465 | 0.87 | F10 (0.49) | F10PRSS1F2PLGPROC | |
| SCHEMBL6278851 | 0.87 | F10 (0.49) | F10PRSS1F2PLGPROC | |
| SCHEMBL7381108 | 0.86 | F10 (0.49) | F10PRSS1F2PLGPROC | |
| SCHEMBL6280041 | 0.85 | F10 (0.54) | F10PRSS1F2PLGPROC | |
| SCHEMBL6278451 | 0.85 | F10 (0.54) | F10PRSS1F2PLGPROC | |
| SCHEMBL7392277 | 0.83 | F10 (0.47) | F10PRSS1F2PLGPROC | |
| SCHEMBL6285035 | 0.83 | F10 (0.47) | F10PRSS1F2PLGPROC | |
| SCHEMBL6279424 | 0.83 | F10 (0.47) | F10PRSS1F2PLGPROC | |
| SCHEMBL6275878 | 0.83 | F10 (0.47) | F10PRSS1F2PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091955-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-1999050263-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | disclosed |