SCHEMBL7357909

SCHEMBL7357909

Clc1ccc(CBr)cc1OC1CCCC1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.55
UTS2R Q9UKP6 6/20 0.41
RECQL P46063 1/20 0.39
HPGD P15428 1/20 0.38
PDE4B Q07343 2/20 0.37
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
KMO O15229 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
NPY1R P25929 1/20 0.35
NPY2R P49146 1/20 0.35
SCD O00767 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7360316 0.81 CSNK2A1 (0.44) CSNK2A1RECQLPDE4BFFAR4NPY1R
SCHEMBL5703607 0.79 PDE4B (0.56) RECQLPDE4B
SCHEMBL3456387 0.79 RECQL (0.60) CSNK2A1RECQLPDE4B
SCHEMBL22816372 0.78 CSNK2A1 (0.47) CSNK2A1HPGDNPY1RNPY2RSLC6A4
SCHEMBL21190898 0.77 CSNK2A1 (0.48) CSNK2A1RECQLPDE4BNPY1RNPY2R
SCHEMBL16695309 0.77 CSNK2A1 (0.46) CSNK2A1HPGDNPY1RNPY2RSLC6A4
SCHEMBL22816048 0.75 CSNK2A1 (0.47) CSNK2A1PDE4BKMO
SCHEMBL7362033 0.75 CSNK2A1 (0.51) CSNK2A1HPGDKMOSCD
SCHEMBL27573105 0.75 CSNK2A1 (0.47) CSNK2A1HPGDPDE4BKMOSCD
SCHEMBL22077713 0.74 SYK (0.48) CSNK2A1UTS2RRECQLPDE4BNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0538384-A4 OXAMIDES SMITHKLINE BEECHAM CORP (US) 1995-04-12 EP disclosed
US-5393788-A Phenylalkyl oxamides SMITHKLINE BEECHAM CORPORATION (US) 1995-02-28 US disclosed
EP-0538384-A1 OXAMIDES SMITHKLINE BEECHAM CORPORATION (US) 1993-04-28 EP disclosed
WO-1992000968-A1 OXAMIDES SMITHKLINE BEECHAM CORPORATION (US) 1992-01-23 WO disclosed