Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 13/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357575 | 0.88 | CACNA1B (0.47) | CACNA1BMEN1KMT2ATDP1OPRD1 | |
| SCHEMBL7353204 | 0.87 | CACNA1B (0.48) | CACNA1BMEN1KMT2AOPRD1 | |
| SCHEMBL7349295 | 0.86 | CACNA1B (0.56) | CACNA1BMEN1KMT2ATDP1OPRD1 | |
| SCHEMBL7354272 | 0.86 | CACNA1B (0.61) | CACNA1BMEN1KMT2A | |
| SCHEMBL7354077 | 0.81 | CACNA1B (0.58) | CACNA1BMEN1KMT2A | |
| SCHEMBL7421288 | 0.81 | CACNA1B (0.49) | CACNA1BOPRD1 | |
| SCHEMBL7042631 | 0.81 | CACNA1B (0.56) | CACNA1BOPRD1 | |
| SCHEMBL7357264 | 0.81 | CACNA1B (0.47) | CACNA1BMEN1KMT2AKDM4E | |
| SCHEMBL7359677 | 0.80 | CACNA1B (0.62) | CACNA1BMEN1KMT2A | |
| SCHEMBL7042629 | 0.80 | CACNA1B (0.43) | CACNA1BGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | claimed |
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |