Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.65 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.55 |
| ▸ | GRM5 | P41594 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | GCK | P35557 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9967900 | 0.89 | MAOB (0.68) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL1426961 | 0.89 | MEN1 (1.00) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL862870 | 0.89 | MEN1 (0.93) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL28515116 | 0.88 | MEN1 (0.60) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| Hydrochloric Acid SCHEMBL6841086 | 0.87 | MEN1 (0.96) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL9454243 | 0.87 | KMT2A (0.59) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL7362723 | 0.87 | HPGD (0.63) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL9967899 | 0.85 | MEN1 (0.57) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL29788233 | 0.84 | MEN1 (0.84) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL10200052 | 0.84 | MEN1 (0.79) | MEN1KMT2ANR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679324-B | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2012-10-03 | — | — | CN | disclosed |
| CN-102482267-A | Substituted benzamide derivatives as glucokinase (GK) activators | CADILA HEALTHCARE LTD | 2012-05-30 | — | — | CN | disclosed |
| CN-102093192-A | Beta-diketone 1-(3,5-dibenzyloxy)phenyl-5-phenylacetylacetone and preparation method thereof | UNIV NORTH CHINA | 2011-06-15 | — | — | CN | disclosed |
| CN-101679324-A | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2010-03-24 | — | — | CN | disclosed |
| CN-101228162-A | 2-phenyl substituted imidazol [4,5b]pyridine/ pyrazine and purine derivatives as glucokinase modulators | ASTRAZENECA AB (SE) | 2008-07-23 | — | — | CN | disclosed |
| WO-1997011960-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1997-04-03 | — | — | WO | disclosed |