SCHEMBL7358331

SCHEMBL7358331

CCCC(=O)NC(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.50
HDAC1 Q13547 3/20 0.50
HDAC2 Q92769 3/20 0.50
HDAC8 Q9BY41 3/20 0.50
HDAC6 Q9UBN7 1/20 0.50
CTSD P07339 1/20 0.48
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ALDH1A1 P00352 2/20 0.40
CASP2 P42575 1/20 0.40
EPHX1 P07099 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
FFAR3 O14843 2/20 0.38
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
HSD17B10 Q99714 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11453491 0.84 HSP90AA1 (0.54) MAPTMEN1KMT2ANPSR1ALDH1A1
SCHEMBL29111619 0.82 HSP90AA1 (0.57) MAPTMEN1KMT2AALDH1A1EPHX1
SCHEMBL11779852 0.82 HSP90AA1 (0.57) MAPTMEN1KMT2AALDH1A1EPHX1
SCHEMBL28667447 0.82 HSP90AA1 (0.57) MAPTMEN1KMT2AALDH1A1EPHX1
SCHEMBL29111627 0.82 HSP90AA1 (0.57) MAPTMEN1KMT2AALDH1A1EPHX1
SCHEMBL29111623 0.82 HSP90AA1 (0.57) MAPTMEN1KMT2AALDH1A1EPHX1
SCHEMBL184487 0.81 HDAC3 (0.46) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL1643947 0.81 HDAC3 (0.63) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL1965844 0.79
Water SCHEMBL29155573 0.78 HDAC3 (0.60) HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101868147-A Fly control method DU PONT 2010-10-20 CN disclosed
CN-101868146-A Ectoparasite control method DU PONT 2010-10-20 CN disclosed
CN-101801191-A Fly control method DU PONT 2010-08-11 CN disclosed
EP-1054877-A1 NOVEL CYCLIC SULFONAMIDE DERIVATIVES AS METALLOPROTEINASE INHIBITORS Du Pont Pharmaceuticals Company (US) 2000-11-29 EP disclosed
WO-1999041246-A1 NOVEL CYCLIC SULFONAMIDE DERIVATIVES AS METALLOPROTEINASE INHIBITORS DU PONT PHARMACEUTICALS COMPANY (US) 1999-08-19 WO disclosed
US-3982891-A Bleaching and detergent compositions having imide activator and peroxygen bleach COLGATE-PALMOLIVE COMPANY (US) 1976-09-28 US disclosed