Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 17/20 | 0.66 |
| ▸ | PLG | P00747 | 8/20 | 0.66 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.66 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.66 |
| ▸ | F2 | P00734 | 7/20 | 0.66 |
| ▸ | PLAT | P00750 | 7/20 | 0.66 |
| ▸ | KLK1 | P06870 | 2/20 | 0.66 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336455 | 0.91 | PLAU (0.78) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7338129 | 0.89 | PLAU (0.67) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7344364 | 0.87 | PLAU (0.65) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7344122 | 0.86 | PLAU (0.84) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7853602 | 0.85 | PLAU (0.70) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7335035 | 0.83 | PLAU (0.63) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7335972 | 0.82 | PLAU (0.56) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL4324160 | 0.80 | PLAU (1.00) | PLAUPLGKLKB1PRSS1F2 | |
| SCHEMBL7340321 | 0.80 | PLAU (1.00) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7335882 | 0.80 | PLAU (0.74) | PLAUPLGKLKB1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258822-B1 | ENZYME INHIBITORS OF NAPHTHALENE AMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-07-10 | — | — | US | disclosed |