Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 16/20 | 0.71 |
| ▸ | PRSS2 | P07478 | 12/20 | 0.71 |
| ▸ | PRSS3 | P35030 | 12/20 | 0.71 |
| ▸ | F10 | P00742 | 9/20 | 0.65 |
| ▸ | PLG | P00747 | 2/20 | 0.65 |
| ▸ | PLAT | P00750 | 2/20 | 0.65 |
| ▸ | F7 | P08709 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7454428 | 0.94 | F2 (0.74) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7365871 | 0.93 | F2 (0.69) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7365373 | 0.93 | F2 (0.71) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7361079 | 0.88 | F2 (0.69) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL7463140 | 0.88 | F2 (0.72) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL7454693 | 0.85 | F2 (0.69) | F2PRSS1PRSS2PRSS3F10 | |
| Hydrochloric Acid SCHEMBL7362150 | 0.85 | F2 (0.57) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7454643 | 0.84 | F2 (1.00) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL7463044 | 0.84 | F2 (0.72) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL7459282 | 0.84 | F2 (0.62) | F2PRSS1PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |