SCHEMBL7360688

SCHEMBL7360688

CC(C)=CCN(c1ccc(CCC2CCCCC2)cc1)C1CCN(CC(C)CC(N)C=O)C1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CACNA1B Q00975 9/20 0.43
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7349827 0.97 CACNA1B (0.42) CACNA1BMAOB
SCHEMBL7354570 0.96 CACNA1B (0.45) CACNA1BMAOB
SCHEMBL7355858 0.91 CACNA1B (0.42) CACNA1B
SCHEMBL7353830 0.89 CACNA1B (0.50) CACNA1BMAOB
SCHEMBL7359802 0.89 CACNA1B (0.42) CACNA1B
SCHEMBL7360274 0.88 CACNA1B (0.42) CACNA1B
SCHEMBL7353835 0.88 CACNA1B (0.42) CACNA1B
SCHEMBL7353813 0.87 CACNA1B (0.46) CACNA1B
SCHEMBL7042875 0.86 CACNA1B (0.47) CACNA1BMAOB
SCHEMBL7042877 0.86 CACNA1B (0.47) CACNA1BMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999007689-A1 ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS WARNER-LAMBERT COMPANY (US) 1999-02-18 WO claimed