Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA9 | Q16790 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 8/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757808 | 0.95 | MAPT (0.63) | CA12CA2CA9MAPTNPSR1 | |
| SCHEMBL548486 | 0.84 | CA12 (1.00) | CA12CA2CA9SMYD3HDAC1 | |
| SCHEMBL7370172 | 0.82 | CA12 (0.58) | CA12CA2CA9MAPTNPSR1 | |
| Ethylene SCHEMBL8378460 | 0.82 | CA12 (0.58) | CA12CA2CA9MAPTNPSR1 | |
| SCHEMBL7559546 | 0.79 | CA12 (0.56) | CA12CA2CA9MAPTNPSR1 | |
| SCHEMBL7555952 | 0.77 | CA12 (0.54) | CA12CA2CA9MAPTNPSR1 | |
| SCHEMBL10576406 | 0.72 | CA12 (0.74) | CA12CA2CA9MAPTNPSR1 | |
| SCHEMBL3282985 | 0.72 | CA12 (0.74) | CA12CA2CA9SMYD3HDAC1 | |
| SCHEMBL5760125 | 0.71 | GRIA3 (1.00) | GRIA3GRIA4HPGDSMN1; SMN2ALDH1A1 | |
| Farampator SCHEMBL677135 | 0.71 | GRIA3 (1.00) | GRIA3GRIA4HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960105-A1 | BENZOFURAZAN COMPOUNDS WHICH ENHANCE AMPA RECEPTOR ACTIVITY | The Regents of the University of California (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998035950-A1 | BENZOFURAZAN COMPOUNDS WHICH ENHANCE AMPA RECEPTOR ACTIVITY | CORTEX PHARMACEUTICALS, INC. (US) | 1998-08-20 | — | — | WO | disclosed |