Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.59 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 4/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.53 |
| ▸ | LAP3 | P28838 | 6/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.51 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.50 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372319 | 0.92 | MME (0.51) | SLC1A3SLC1A2SLC1A1ANPEPMME | |
| SCHEMBL5059848 | 0.81 | FOLH1 (0.69) | ANPEPERAP2LAP3ERAP1FOLH1 | |
| SCHEMBL20549732 | 0.81 | ERAP1 (0.47) | SLC1A3SLC1A2SLC1A1ANPEPERAP2 | |
| SCHEMBL28522482 | 0.81 | ERAP1 (0.47) | SLC1A3SLC1A2SLC1A1ANPEPERAP2 | |
| SCHEMBL23497863 | 0.80 | MME (0.67) | ANPEPMME | |
| SCHEMBL30602602 | 0.80 | MME (0.67) | ANPEPMME | |
| Phenylalanine SCHEMBL4958178 | 0.76 | SLC7A5 (0.85) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| Dl-Phenylalanine SCHEMBL4958176 | 0.76 | SLC7A5 (0.85) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL7442040 | 0.75 | ERAP2 (0.51) | ANPEPERAP2LAP3ERAP1FOLH1 | |
| Dl-Phenylalanine SCHEMBL7645387 | 0.75 | SLC7A5 (0.81) | SLC1A3SLC1A2SLC1A1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |