Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 17/20 | 0.46 |
| ▸ | PLG | P00747 | 8/20 | 0.45 |
| ▸ | PLAT | P00750 | 4/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7372950 | 0.90 | PLAU (0.50) | PLAUPLGPLATPDK1PDK2 | |
| SCHEMBL6437441 | 0.86 | PLAU (0.57) | PLAUPLGPLAT | |
| SCHEMBL6432761 | 0.79 | PLAU (0.51) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6433179 | 0.79 | PLAU (0.46) | PLAUPLGPLAT | |
| SCHEMBL6434840 | 0.79 | PLAU (0.53) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6432757 | 0.79 | PLAU (0.50) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6437300 | 0.79 | PLAU (0.68) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6439060 | 0.78 | PLAU (0.55) | PLAUPLGPLAT | |
| SCHEMBL6433837 | 0.78 | PLAU (0.51) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL7457006 | 0.78 | PLAU (0.48) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |
| EP-1077945-A1 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000005214-A2 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2000-02-03 | — | — | WO | disclosed |