Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501523 | 0.88 | DAO (0.40) | HPGDALDH1A1KDM4EGAAHDAC3 | |
| SCHEMBL277557 | 0.84 | HPGD (0.46) | HPGDL3MBTL1MAPK1ATMNPSR1 | |
| SCHEMBL13812359 | 0.80 | HPGD (0.44) | HPGDL3MBTL1MAPK1ATMNPSR1 | |
| SCHEMBL28211212 | 0.75 | HPGD (0.46) | HPGDL3MBTL1MAPK1ATMNPSR1 | |
| SCHEMBL70027 | 0.74 | NPSR1 (0.67) | HPGDL3MBTL1MAPK1ATMNPSR1 | |
| SCHEMBL1587411 | 0.73 | NPSR1 (0.53) | HPGDL3MBTL1MAPK1ATMNPSR1 | |
| SCHEMBL24716783 | 0.72 | HPGD (0.43) | HPGDL3MBTL1MAPK1ATMNPSR1 | |
| SCHEMBL2847199 | 0.72 | HPGD (0.46) | HPGDL3MBTL1MAPK1ATMNPSR1 | |
| SCHEMBL8549434 | 0.72 | TSHR (0.44) | HPGDL3MBTL1MAPK1ATMNPSR1 | |
| SCHEMBL7979113 | 0.71 | HPGD (0.42) | HPGDL3MBTL1MAPK1ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091952-A1 | THIOPHENE AND FURAN 2,5-DICARBOXAMIDES USEFUL IN THE TREATMENT OF CANCER | BIOCHEM PHARMA INC (CA) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000486-A1 | THIOPHENE AND FURAN 2,5-DICARBOXAMIDES USEFUL IN THE TREATMENT OF CANCER | BIOCHEM PHARMA INC. (US) | 2000-01-06 | — | — | WO | disclosed |