Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43676 | 0.88 | KCNA3 (0.58) | KCNA3PKMALDH1A1TAAR1RECQL | |
| SCHEMBL2069623 | 0.84 | KCNA3 (0.54) | KCNA3PKMALDH1A1TAAR1RECQL | |
| SCHEMBL11087417 | 0.83 | KCNA3 (0.70) | KCNA3PKMALDH1A1TAAR1RECQL | |
| SCHEMBL5067163 | 0.83 | KCNA3 (0.70) | KCNA3PKMALDH1A1TAAR1RECQL | |
| SCHEMBL10452423 | 0.83 | KCNA3 (0.70) | KCNA3PKMALDH1A1TAAR1RECQL | |
| SCHEMBL148066 | 0.83 | KCNA3 (0.70) | KCNA3PKMALDH1A1TAAR1RECQL | |
| SCHEMBL2481801 | 0.83 | KCNA3 (0.70) | KCNA3PKMALDH1A1TAAR1RECQL | |
| SCHEMBL466750 | 0.83 | KCNA3 (0.70) | KCNA3PKMALDH1A1TAAR1RECQL | |
| SCHEMBL96853 | 0.82 | KCNA3 (0.62) | KCNA3PKMALDH1A1TAAR1RECQL | |
| SCHEMBL11322786 | 0.81 | KCNA3 (0.50) | KCNA3PKMALDH1A1TAAR1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | disclosed |