Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.63 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7243724 | 0.86 | ESR2 (0.48) | ESR2SLC18A3SIGMAR1GRIN2BSRD5A1 | |
| SCHEMBL190417 | 0.79 | SLC18A3 (0.67) | SLC18A3SIGMAR1GRIN2BDRD2KDM4E | |
| SCHEMBL41763 | 0.79 | — | — | |
| SCHEMBL18257853 | 0.77 | ESR2 (1.00) | ESR2 | |
| Benzene SCHEMBL23070411 | 0.76 | SLC18A3 (0.64) | SLC18A3SIGMAR1GRIN2BDRD2KDM4E | |
| Hydrogen Peroxide SCHEMBL2353767 | 0.76 | SLC18A3 (0.64) | SLC18A3SIGMAR1GRIN2B | |
| Ammonia Solution, Strong SCHEMBL3932661 | 0.76 | SLC18A3 (0.64) | SLC18A3SIGMAR1GRIN2BDRD2KDM4E | |
| Hydrochloric Acid SCHEMBL29241797 | 0.76 | SLC18A3 (0.64) | SLC18A3SIGMAR1GRIN2BDRD2 | |
| SCHEMBL20010634 | 0.76 | SLC18A3 (0.52) | SLC18A3SIGMAR1GRIN2BSRD5A1DRD2 | |
| SCHEMBL9253267 | 0.76 | SLC18A3 (0.52) | SLC18A3SIGMAR1GRIN2BSRD5A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466874-A | Preparation method of indole-containing polysubstituted tetrahydrofuran compound | 扬州大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-106588807-B | Alkene compound containing gem-difluoromethylene and preparation method thereof | 上海大学 | 2020-04-03 | — | — | CN | disclosed |
| CN-106588807-A | Olefin compound containing gem-difluoro-methylene and preparing method thereof | 上海大学 | 2017-04-26 | — | — | CN | disclosed |
| US-20170101388-A1 | C-GLYCOSIDE DERIVATIVE | Xuanzhu Pharma Co., Ltd. (CN) | 2017-04-13 | — | — | US | disclosed |
| US-9562029-B2 | C-glycoside derivatives | Xuanzhu Pharma Co., Ltd. (CN) | 2017-02-07 | — | — | US | disclosed |
| US-6329400-B1 | INHIBITION OR ANTAGONISM OF MATRIX METALLOPROTEASES, AND/OR TUMOR NECROSIS FACTOR-ALPHA; EXTRACELLULAR MATRIX DEGRADATION, INHIBITION OF SHEDDING OF CELL SURFACE PROTEIN ECTODOMAINS AND CD23 PROTEOLYSIS | GLAXO WELLCOME INC. | 2001-12-11 | — | — | US | disclosed |
| WO-2000012082-A1 | FORMAMIDE COMPOUNDS AS THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| US-4849574-A | Synthesis of olefins from ketones or aldehydes using bis(alkylchloroalumino)methane | TEXAS ALKYLS, INC. (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0318073-A1 | Synthesis of olefins from ketones using organoaluminium compounds | TEXAS ALKYLS, INC. (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4788367-A | Synthesis of olefins from ketones using bis(alkylchloroalumino)methane | TEXAS ALKYLS INC. (US) | 1988-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101388-A1 | C-GLYCOSIDE DERIVATIVE | RDX, C1R, C3AR1 | ESR2 883/4885SLC18A3 3261/4885SIGMAR1 1912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.