Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.60 |
| ▸ | F2 | P00734 | 14/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361040 | 0.92 | F10 (0.58) | F10F2PRSS1KCNA5 | |
| SCHEMBL7362516 | 0.89 | F10 (0.67) | F10F2PRSS1KCNA5 | |
| SCHEMBL7360285 | 0.87 | F10 (0.71) | F10F2PRSS1 | |
| SCHEMBL7361243 | 0.84 | F10 (0.69) | F10F2PRSS1KCNA5 | |
| SCHEMBL7360144 | 0.82 | F10 (0.61) | F10F2PRSS1 | |
| SCHEMBL7364249 | 0.82 | F2 (0.62) | F10F2PRSS1KCNA5 | |
| SCHEMBL7365982 | 0.82 | F2 (0.58) | F10F2PRSS1KCNA5FFAR1 | |
| SCHEMBL7367197 | 0.81 | F2 (0.71) | F10F2PRSS1 | |
| SCHEMBL7361112 | 0.79 | HTT (0.54) | F10F2PRSS1KCNA5 | |
| SCHEMBL7686273 | 0.79 | KCNA5 (0.47) | F10F2PRSS1KCNA5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5942544-A | α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |