⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013400 | 0.71 | — | — | |
| SCHEMBL9769061 | 0.69 | — | — | |
| SCHEMBL27508521 | 0.67 | — | — | |
| SCHEMBL28326768 | 0.67 | — | — | |
| SCHEMBL5150721 | 0.67 | — | — | |
| SCHEMBL1013399 | 0.67 | — | — | |
| SCHEMBL4097458 | 0.67 | — | — | |
| SCHEMBL7363362 | 0.67 | — | — | |
| SCHEMBL11993132 | 0.67 | — | — | |
| SCHEMBL12104473 | 0.63 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383856-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2024-11-21 | — | — | US | claimed |
| CN-105849104-A | Strigolactone formulations and uses thereof | 阿西洛玛生物公司 | 2016-08-10 | — | — | CN | claimed |
| EP-0815108-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-07 | — | — | EP | claimed |
| US-5683999-A | Cyclic urea HIV protease inhibitors | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-11-04 | — | — | US | claimed |
| WO-1996029329-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-26 | — | — | WO | claimed |
| CN-117534639-A | Amide compound, preparation method and agronomic application thereof | 南开大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-110734417-B | 2-butenolide acetamide compound and preparation method and application thereof | 南开大学 | 2022-09-30 | — | — | CN | disclosed |
| WO-2020023657-A1 | PYRIDIN-2-ONE COMPOUNDS USEFUL AS SMARCA2 ANTAGONISTS | Epizyme, Inc. (US) | 2020-01-30 | — | — | WO | disclosed |
| WO-2019059161-A1 | PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL GERMICIDE HAVING SAME AS ACTIVE INGREDIENT | 三井化学アグロ株式会社 | 2019-03-28 | — | — | WO | disclosed |
| CN-102015641-A | Heterocyclic compound | TAKEDA PHARMACEUTICAL | 2011-04-13 | — | — | CN | disclosed |
| CN-1185156-A | Novel substituted tetrahydropyrano [3, 2-d ] oxazolones, process for their preparation and pharmaceutical compositions containing them | ADIR ET CO (FR) | 1998-06-17 | — | — | CN | disclosed |
| EP-0822936-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRANO 3,2-d]OXAZOLONES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-02-11 | — | — | EP | disclosed |
| EP-0815108-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5683999-A | Cyclic urea HIV protease inhibitors | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-11-04 | — | — | US | disclosed |
| WO-1996033999-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRANO[3,2-d]OXAZOLONES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1996-10-31 | — | — | WO | disclosed |
| WO-1996029329-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-26 | — | — | WO | disclosed |