Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257301 | 0.69 | — | — | |
| SCHEMBL9423146 | 0.69 | — | — | |
| SCHEMBL29581947 | 0.67 | MAPT (0.41) | AKT1 | |
| SCHEMBL29281154 | 0.66 | — | — | |
| SCHEMBL29281155 | 0.66 | — | — | |
| SCHEMBL20286038 | 0.64 | — | — | |
| SCHEMBL382020 | 0.63 | PTPN1 (0.36) | AKT1 | |
| SCHEMBL8749939 | 0.58 | — | — | |
| SCHEMBL583681 | 0.54 | — | — | |
| SCHEMBL22500190 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060600-A | TREATMENT OF AIDS AND OTHER DISEASES CAUSED BY RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| US-5977169-A | FOR TREATMENT OF A PERSON WITH AIDS OR AIDS RELATED DISEASES | PHARMACIA & UPJOHN COMPANY | 1999-11-02 | — | — | US | disclosed |
| WO-1996029333-A1 | SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1996-09-26 | — | — | WO | disclosed |
| WO-1995007901-A1 | SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1995-03-23 | — | — | WO | disclosed |