Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363763 | 1.00 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2KCNA3EPHX1 | |
| SCHEMBL7363761 | 1.00 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2KCNA3EPHX1 | |
| SCHEMBL7369953 | 0.82 | EPHX1 (0.57) | SLC6A4SLC6A3SLC6A2EPHX1MEN1 | |
| SCHEMBL3594490 | 0.82 | EPHX1 (0.57) | SLC6A4SLC6A3SLC6A2EPHX1MEN1 | |
| SCHEMBL3595876 | 0.82 | EPHX1 (0.57) | SLC6A4SLC6A3SLC6A2EPHX1MEN1 | |
| SCHEMBL13405028 | 0.81 | CHRM1 (0.52) | SLC6A4SLC6A3SLC6A2EPHX1 | |
| SCHEMBL6009309 | 0.80 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| SCHEMBL6007356 | 0.80 | HTR2A (0.61) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4350813 | 0.80 | EPHX1 (0.55) | SLC6A4SLC6A3SLC6A2EPHX1RAB9A | |
| SCHEMBL11991373 | 0.80 | EPHX1 (0.55) | SLC6A4SLC6A3EPHX1RAB9AANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |