⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15466711 | 1.00 | — | — | |
| SCHEMBL7363817 | 1.00 | — | — | |
| SCHEMBL1761782 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1761547 | 0.97 | — | — | |
| SCHEMBL16076278 | 0.72 | — | — | |
| SCHEMBL16033260 | 0.72 | CYP2C9 (0.48) | — | |
| SCHEMBL14872327 | 0.72 | CYP2C9 (0.48) | — | |
| SCHEMBL16033262 | 0.72 | CYP2C9 (0.48) | — | |
| SCHEMBL1841914 | 0.72 | CYP2C9 (0.48) | — | |
| SCHEMBL16076275 | 0.72 | CYP2C9 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530353-A1 | NEW IMIDAZOPYRIDINES AS SEROTONERGIC 5-HT 3? ANTAGONISTS | G.D. SEARLE & CO. (US) | 1993-03-10 | — | — | EP | disclosed |
| EP-0504679-A1 | New imidazopyridines as serotonergic 5-HT3 antagonists | G.D. Searle & Co. (US) | 1992-09-23 | — | — | EP | disclosed |
| WO-1992015593-A1 | NEW IMIDAZOPYRIDINES AS SEROTONERGIC 5-HT3 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | disclosed |