Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL25206795 | 0.84 | SLC7A5 (0.60) | SLC7A5SLC1A3SLC1A2SLC1A1NOS1 | |
| Valine SCHEMBL28911782 | 0.83 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1NOS1 | |
| Valine SCHEMBL28911785 | 0.83 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1NOS1 | |
| Valine SCHEMBL15602719 | 0.78 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| Valine SCHEMBL27571970 | 0.78 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL2800672 | 0.78 | — | — | |
| Valine SCHEMBL41225 | 0.78 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| Valine SCHEMBL1813972 | 0.78 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| Valine SCHEMBL8516 | 0.78 | — | — | |
| Valine SCHEMBL288203 | 0.78 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997011960-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1997-04-03 | — | — | WO | disclosed |