SCHEMBL7364253

SCHEMBL7364253

CCCOc1ccccc1S(=O)(=O)N(c1cc(C)cc(OCCNc2c(Cl)cnnc2Cl)c1)C(C)(C)P(=O)=O

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F2 P00734 6/20 0.40
PRSS2 P07478 1/20 0.32
CTRC Q99895 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8728910 0.96 F2 (0.39) F2PRSS2CTRC
SCHEMBL8726831 0.95 F2 (0.40) F2PRSS2CTRC
SCHEMBL8732984 0.93 F2 (0.47) F2PRSS2CTRC
SCHEMBL8732116 0.91 F2 (0.39) F2PRSS2CTRC
SCHEMBL7390311 0.90 F2 (0.40) F2PRSS2CTRC
SCHEMBL8726758 0.86 F2 (0.39) F2PRSS2CTRC
SCHEMBL7391086 0.85 F2 (0.40) F2PRSS2CTRC
SCHEMBL8726814 0.84 F2 (0.48) F2PRSS2CTRC
SCHEMBL8726738 0.83 F2 (0.58) F2PRSS2CTRC
SCHEMBL7356698 0.82 F2 (0.47) F2PRSS2CTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778839-B1 NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS BOEHRINGER MANNHEIM GMBH (DE) 1998-12-23 EP disclosed
US-5824679-A Phosphanoxides--preparation and use BOEHRINGER MANNHEIM GMBH (DE) 1998-10-20 US disclosed
EP-0778839-A1 NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS Roche Diagnostics GmbH (DE) 1997-06-18 EP disclosed
WO-1996006849-A1 NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS BOEHRINGER MANNHEIM GMBH (DE) 1996-03-07 WO disclosed