Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739438 | 0.83 | KDM4E (0.49) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL29178984 | 0.83 | KDM4E (0.49) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL10463716 | 0.82 | KDM4E (0.51) | KDM4EHPGDSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL10518642 | 0.79 | KDM4E (0.50) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL10463714 | 0.78 | CYP1A2 (0.45) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL10462312 | 0.77 | KDM4E (0.44) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL22431574 | 0.77 | KDM4E (0.52) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL13317085 | 0.77 | KDM4E (0.60) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL10463812 | 0.76 | KDM4E (0.48) | KDM4ENPC1LMNATP53HPGD | |
| SCHEMBL10462306 | 0.76 | CYP1A2 (0.49) | KDM4ENPC1LMNATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466915-A | Chromone-containing benzo [ d ] imidazo [2,1-b ] thiazole compound and preparation method and application thereof | 江西科技师范大学 | 2024-01-30 | — | — | CN | claimed |
| CN-117466915-A | Chromone-containing benzo [ d ] imidazo [2,1-b ] thiazole compound and preparation method and application thereof | 江西科技师范大学 | 2024-01-30 | — | — | CN | disclosed |
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | disclosed |
| EP-0757692-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029922-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |
| US-4968708-A | Imidazo[2,1-B]benzothiazole compounds and antiulcer compositions containing the same | NIKKEN CHEMICALS CO., LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0347880-A2 | Imidazo[2,1-b]benzothiazole compounds and antiulcer compositions containing the same | NIKKEN CHEMICALS CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |