Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 11/20 | 0.55 |
| ▸ | YAP1 | P46937 | 5/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195243 | 0.91 | CACNA1B (0.59) | CACNA1BYAP1MMEACECPA1 | |
| SCHEMBL7399075 | 0.91 | CACNA1B (0.51) | CACNA1BMMEACECPA1ACE2 | |
| SCHEMBL7398580 | 0.90 | CACNA1B (0.50) | CACNA1BYAP1CTSKMMEACE | |
| SCHEMBL7402922 | 0.89 | CACNA1B (0.49) | CACNA1BUTS2RMMEACECPA1 | |
| SCHEMBL7343479 | 0.84 | CACNA1B (0.55) | CACNA1BYAP1MMEACECPA1 | |
| SCHEMBL7402336 | 0.83 | CACNA1B (0.55) | CACNA1BYAP1 | |
| SCHEMBL8188856 | 0.82 | UTS2R (0.54) | YAP1UTS2R | |
| SCHEMBL5833508 | 0.82 | CACNA1B (0.52) | CACNA1BYAP1MMEACECPA1 | |
| SCHEMBL7408660 | 0.82 | UTS2R (0.59) | UTS2R | |
| SCHEMBL7405382 | 0.82 | CACNA1B (0.57) | CACNA1BYAP1MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | claimed |
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |