Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018725 | 1.00 | CA1 (0.57) | CA1CA2CA7CYP2D6CTSS | |
| SCHEMBL10982144 | 0.87 | CA1 (0.57) | CA1CA2CA7CYP2D6CTSS | |
| SCHEMBL14923548 | 0.86 | CA1 (0.54) | CA1CA2CA7CYP2D6CTSS | |
| SCHEMBL14980856 | 0.86 | CA1 (0.54) | CA1CA2CA7CYP2D6CTSS | |
| SCHEMBL10727796 | 0.86 | CA1 (0.55) | CA1CA2CA7CYP2D6CTSS | |
| SCHEMBL6490683 | 0.86 | CA1 (0.55) | CA1CA2CA7CYP2D6CTSS | |
| SCHEMBL5170605 | 0.86 | CA1 (0.55) | CA1CA2CA7CYP2D6CTSS | |
| SCHEMBL6487911 | 0.86 | CA1 (0.55) | CA1CA2CA7CYP2D6CTSS | |
| SCHEMBL10573143 | 0.85 | CA1 (0.62) | CA1CA2CA7CYP2D6CTSS | |
| SCHEMBL15614935 | 0.85 | CA1 (0.62) | CA1CA2CA7CYP2D6CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |