Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.50 |
| ▸ | F10 | P00742 | 6/20 | 0.45 |
| ▸ | F7 | P08709 | 3/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | PLAT | P00750 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360775 | 0.93 | F2 (0.53) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL7454841 | 0.85 | F2 (0.60) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7363749 | 0.81 | F2 (0.59) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7362467 | 0.81 | FFAR1 (0.53) | GMNNALDH1A1LMNACYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL7362150 | 0.79 | F2 (0.57) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7365871 | 0.79 | F2 (0.69) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL7450712 | 0.79 | F2 (0.67) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL7459282 | 0.79 | F2 (0.62) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL7463140 | 0.79 | F2 (0.72) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7364865 | 0.78 | SMN1; SMN2 (0.39) | F2PRSS1PRSS2PRSS3GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |