Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | MME | P08473 | 2/20 | 0.55 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365027 | 1.00 | ACE (0.55) | ACEMMEMMEL1ECE1 | |
| SCHEMBL7365025 | 1.00 | ACE (0.55) | ACEMMEMMEL1ECE1 | |
| SCHEMBL7363834 | 0.87 | HRH4 (0.53) | ACEMMEECE1 | |
| SCHEMBL7363831 | 0.87 | HRH4 (0.53) | ACEMMEECE1 | |
| SCHEMBL7363836 | 0.87 | HRH4 (0.53) | ACEMMEECE1 | |
| SCHEMBL7368279 | 0.83 | ACE (0.65) | ACEMMEMMEL1ECE1 | |
| SCHEMBL9069494 | 0.81 | ACE (0.61) | ACEMMEMMEL1ECE1 | |
| SCHEMBL7372720 | 0.81 | ACE (0.63) | ACEMMEMMEL1ECE1 | |
| SCHEMBL7364336 | 0.80 | POLB (0.53) | — | |
| SCHEMBL4116935 | 0.80 | POLB (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |