Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435656 | 0.98 | CYP2C19 (0.50) | CYP2C19MMEFFAR3 | |
| SCHEMBL6639985 | 0.82 | CYP2C19 (0.31) | CYP2C19 | |
| SCHEMBL4814568 | 0.81 | — | — | |
| SCHEMBL8278870 | 0.77 | CYP2C19 (0.54) | CYP2C19MMEFFAR3CYP4F2CYP4A11 | |
| SCHEMBL7364717 | 0.74 | CYP4F2 (0.38) | CYP4F2CYP4A11 | |
| SCHEMBL7435851 | 0.72 | CYP2C19 (0.31) | CYP2C19 | |
| SCHEMBL6876483 | 0.72 | CYP2C19 (0.48) | CYP2C19MME | |
| SCHEMBL6735060 | 0.72 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL7507864 | 0.71 | CYP2C19 (0.64) | CYP2C19MMEFFAR3CYP4F2CYP4A11 | |
| SCHEMBL1812100 | 0.70 | CYP2C19 (0.56) | CYP2C19MMEFFAR3CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407960-A | For cardiovascualr disorders, pain | SCHERING CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |
| WO-1991009840-A1 | MERCAPTOCYCLOACYL AMINOACID ENDOPEPTIDASE INHIBITORS | SCHERING CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |