Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 18/20 | 0.49 |
| ▸ | PDE2A | O00408 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499453 | 1.00 | PDE5A (0.49) | PDE5APDE2AGAALMNAHPGD | |
| SCHEMBL7367995 | 0.92 | PDE5A (0.54) | PDE5APDE2AGAA | |
| SCHEMBL7397184 | 0.91 | PDE5A (0.60) | PDE5APDE2AGAA | |
| SCHEMBL7397182 | 0.91 | PDE5A (0.60) | PDE5APDE2AGAA | |
| SCHEMBL7369160 | 0.85 | PPARA (0.47) | PDE5AGAALMNAHPGD | |
| SCHEMBL7367389 | 0.85 | PDE5A (0.46) | PDE5APDE2AGAA | |
| SCHEMBL7404535 | 0.84 | PDE5A (0.51) | PDE5APDE2ALMNA | |
| SCHEMBL7404538 | 0.84 | PDE5A (0.51) | PDE5APDE2ALMNA | |
| SCHEMBL7404179 | 0.81 | PDE5A (0.48) | PDE5APDE2A | |
| SCHEMBL8292542 | 0.81 | PDE5A (0.53) | PDE5APDE2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |