Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 6/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791466 | 0.96 | MAPK1 (0.48) | EPHX1MAPK1GAAHTTSMN1; SMN2 | |
| SCHEMBL31580592 | 0.96 | MAPK1 (0.48) | EPHX1MAPK1GAAHTTSMN1; SMN2 | |
| SCHEMBL29842368 | 0.96 | MAPK1 (0.48) | EPHX1MAPK1GAAHTTSMN1; SMN2 | |
| SCHEMBL966084 | 0.92 | MAPK1 (0.53) | EPHX1MAPK1GAAHTTSMN1; SMN2 | |
| SCHEMBL967534 | 0.90 | MAPK1 (0.55) | EPHX1MAPK1GAAHTTSMN1; SMN2 | |
| SCHEMBL968142 | 0.90 | MAPK1 (0.55) | EPHX1MAPK1GAAHTTSMN1; SMN2 | |
| SCHEMBL967232 | 0.90 | MAPK1 (0.55) | EPHX1MAPK1GAAHTTSMN1; SMN2 | |
| SCHEMBL28229178 | 0.90 | GAA (0.50) | EPHX1MAPK1GAAHTTSMN1; SMN2 | |
| SCHEMBL951710 | 0.90 | GAA (0.50) | EPHX1MAPK1GAAHTTSMN1; SMN2 | |
| SCHEMBL28246288 | 0.90 | GAA (0.50) | EPHX1MAPK1GAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042656-A1 | NOVEL COMPOUNDS | CYTEL CORPORATION (US) | 1998-10-01 | — | — | WO | disclosed |