Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068478 | 0.90 | POLB (0.53) | POLBPLGHDAC8DDB1CRBN | |
| Succinic Acid SCHEMBL9425281 | 0.82 | POLB (0.45) | POLBPLGHDAC8DDB1CRBN | |
| Succinic Acid SCHEMBL9425597 | 0.82 | POLB (0.45) | POLBPLGHDAC8DDB1CRBN | |
| Succinic Acid SCHEMBL9425252 | 0.82 | POLB (0.45) | POLBPLGHDAC8DDB1CRBN | |
| Succinic Acid SCHEMBL9426818 | 0.81 | POLB (0.44) | POLBPLGHDAC8DDB1CRBN | |
| Tert-Butyl Formate SCHEMBL27853000 | 0.77 | POLB (0.40) | POLBPLGHDAC8DDB1CRBN | |
| SCHEMBL7365623 | 0.75 | BRD4 (0.35) | POLB | |
| SCHEMBL167189 | 0.75 | POLB (0.89) | POLBGBA1LTA4H | |
| SCHEMBL167190 | 0.75 | POLB (0.89) | POLBGBA1LTA4H | |
| SCHEMBL1860551 | 0.75 | POLB (0.89) | POLBGBA1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882739-A1 | NEW ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland UC (IE) | 2015-06-17 | — | — | EP | disclosed |
| EP-2742044-A1 | ANTIBACTERIAL HOMOPIPERIDINYL SUBSTITUTED 3,4 DIHYDRO 1H [1,8]NAPHTHYRIDINONES | Janssen R&D Ireland (IE) | 2014-06-18 | — | — | EP | disclosed |
| WO-2014023815-A1 | NEW ANTIBACTERIAL COMPOUNDS | JANSSEN R&D IRELAND (IE) | 2014-02-13 | — | — | WO | disclosed |
| WO-2013021051-A1 | ANTIBACTERIAL HOMOPIPERIDINYL SUBSTITUTED 3,4 DIHYDRO 1H [1,8]NAPHTHYRIDINONES | JANSSEN R&D IRELAND (IE) | 2013-02-14 | — | — | WO | disclosed |
| EP-1250337-A1 | SUBSTITUTED HOMOPIPERIDINYL BENZIMIDAZOLE ANALOGUES AS FUNDIC RELAXANTS | Janssen Pharmaceutica N.V. (BE) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001046189-A1 | SUBSTITUTED HOMOPIPERIDINYL BENZIMIDAZOLE ANALOGUES AS FUNDIC RELAXANTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-06-28 | — | — | WO | disclosed |
| WO-1997048702-A1 | BENZAZEPINE DERIVATIVES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PRODUCTION | DR. KARL THOMAE GMBH (DE) | 1997-12-24 | — | — | WO | disclosed |