Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.51 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | XIAP | P98170 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395725 | 0.91 | CAPN1 (0.48) | CTSLCTSBCTSKCAPN1CCR1 | |
| SCHEMBL7356416 | 0.90 | PREP (0.49) | CTSKCAPN1ACE | |
| SCHEMBL3729400 | 0.86 | ACE (0.57) | XIAPACE | |
| SCHEMBL7269341 | 0.86 | ACE (0.57) | XIAPACE | |
| SCHEMBL13260016 | 0.83 | XIAP (0.54) | CTSLCTSBCTSKCAPN1CCR1 | |
| SCHEMBL3722619 | 0.83 | XIAP (0.54) | CTSLCTSBCTSKCAPN1CCR1 | |
| SCHEMBL10879562 | 0.81 | ACE (0.48) | ACE | |
| SCHEMBL10646920 | 0.79 | NPC1 (0.52) | ACE | |
| SCHEMBL7475934 | 0.79 | NPC1 (0.52) | ACE | |
| SCHEMBL9608877 | 0.76 | XIAP (0.51) | CTSLCTSBCTSKCAPN1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051301-A1 | 1-Carboxy-azaalkyl-indolin-2-carboxylic acids, process for preparing them, pharmaceutical compositions containing them and their therapeutical use | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |