Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366809 | 0.90 | PDE4A (0.64) | PDE4AKCNH2 | |
| SCHEMBL7359822 | 0.89 | PDE4A (0.66) | PDE4AKCNH2 | |
| SCHEMBL7952889 | 0.86 | PDE4A (0.63) | PDE4AKCNH2 | |
| SCHEMBL7376251 | 0.85 | PDE4A (0.67) | PDE4AKCNH2 | |
| SCHEMBL7380926 | 0.82 | PDE4A (0.76) | PDE4AKCNH2 | |
| SCHEMBL7899075 | 0.81 | PDE4A (0.88) | PDE4AKCNH2 | |
| SCHEMBL7382646 | 0.81 | PDE4A (0.67) | PDE4AKCNH2 | |
| SCHEMBL7359815 | 0.81 | PDE4A (0.65) | PDE4AKCNH2 | |
| SCHEMBL7376254 | 0.80 | PDE4A (0.66) | PDE4AKCNH2 | |
| SCHEMBL7364400 | 0.80 | PDE4A (0.69) | PDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804603-A1 | BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE | President and Fellows of Harvard College (US) | 2014-11-26 | — | — | EP | claimed |
| WO-2013106547-A1 | BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-07-18 | — | — | WO | claimed |
| JP-2002544259-A | — | — | 2002-12-24 | — | — | JP | claimed |
| EP-1189888-A1 | HETEROSUBSTITUTED PYRIDINE DERIVATIVES AS $i(PDE 4) INHIBITORS | Merck Frosst Canada & Co. (CA) | 2002-03-27 | — | — | EP | claimed |
| WO-2000069824-A1 | HETEROSUBSTITUTED PYRIDINE DERIVATIVES AS PDE 4 INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2000-11-23 | — | — | WO | claimed |
| EP-2804603-A1 | BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE | President and Fellows of Harvard College (US) | 2014-11-26 | — | — | EP | disclosed |
| WO-2013106547-A1 | BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-07-18 | — | — | WO | disclosed |
| EP-1189888-A1 | HETEROSUBSTITUTED PYRIDINE DERIVATIVES AS $i(PDE 4) INHIBITORS | Merck Frosst Canada & Co. (CA) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000069824-A1 | HETEROSUBSTITUTED PYRIDINE DERIVATIVES AS PDE 4 INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2000-11-23 | — | — | WO | disclosed |