⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896543 | 0.65 | — | — | |
| SCHEMBL3175478 | 0.65 | — | — | |
| SCHEMBL3466853 | 0.63 | — | — | |
| SCHEMBL4195223 | 0.61 | — | — | |
| SCHEMBL7371532 | 0.61 | — | — | |
| SCHEMBL3269264 | 0.61 | — | — | |
| SCHEMBL3269258 | 0.61 | — | — | |
| SCHEMBL7039065 | 0.60 | — | — | |
| SCHEMBL305863 | 0.58 | — | — | |
| SCHEMBL7760419 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137889-A | Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5034395-A | Hypotensive agents, carboxylated dihydropyridines | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0114576-B1 | PERFLUOROALKYL-ALKYLENE BRANCHED AMPHOTERIC SULFATO BETAINES | CIBA-GEIGY AG (CH) | 1987-04-22 | — | — | EP | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| EP-0114576-A2 | Perfluoroalkyl-alkylene branched amphoteric sulfato betaines | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | disclosed |