Dichlorophen

Dichlorophen

SCHEMBL7366489

CCOC(N)=O.Oc1ccc(Cl)cc1Cc1cc(Cl)ccc1O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.61
MEN1 O00255 4/20 0.61
ALOX15 P16050 4/20 0.61
HIF1A Q16665 3/20 0.61
HPGD P15428 3/20 0.61
CYP3A4 P08684 3/20 0.61
MAPT P10636 3/20 0.61
USP2 O75604 2/20 0.61
CASP1 P29466 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
SLC22A1 O15245 1/20 0.61
LMNA P02545 1/20 0.61
HSP90AA1 P07900 1/20 0.61
HSPD1 P10809 1/20 0.61
HSPA5 P11021 1/20 0.61
IDO1 P14902 1/20 0.61
ALOX12 P18054 1/20 0.61
HTT P42858 1/20 0.61
BLM P54132 1/20 0.61
HSPE1 P61604 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dichlorophen SCHEMBL20485102 0.85 KMT2A (0.53) KMT2AMEN1ALOX15HIF1AHPGD
SCHEMBL7364590 0.79 MAPT (0.61) KMT2AMEN1ALOX15HIF1AHPGD
Dichlorophen SCHEMBL2453304 0.78 CYP3A4 (0.83) KMT2AMEN1ALOX15HIF1AHPGD
SCHEMBL6076931 0.78 MEN1 (0.57) KMT2AMEN1ALOX15HIF1AHPGD
SCHEMBL27722021 0.78 MEN1 (0.51) KMT2AMEN1ALOX15HIF1AHPGD
Dichlorophen SCHEMBL16619827 0.78 CYP3A4 (0.91) KMT2AMEN1ALOX15HIF1AHPGD
Dichlorophen SCHEMBL18052 0.78 CYP3A4 (1.00) KMT2AMEN1ALOX15HIF1AHPGD
Dichlorophen SCHEMBL9109126 0.78 CYP3A4 (1.00) KMT2AMEN1ALOX15HIF1AHPGD
Dichlorophen SCHEMBL29524636 0.78 CYP3A4 (1.00) KMT2AMEN1ALOX15HIF1AHPGD
Dichlorophen SCHEMBL29349447 0.78 CYP3A4 (1.00) KMT2AMEN1ALOX15HIF1AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0578745-A1 PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES THE UPJOHN COMPANY (US) 1994-01-19 EP disclosed
WO-1992017490-A1 PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES THE UPJOHN COMPANY (US) 1992-10-15 WO disclosed