Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.82 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.82 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.82 |
| ▸ | MAOB | P27338 | 7/20 | 0.76 |
| ▸ | BCHE | P06276 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.68 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | TGM2 | P21980 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454702 | 1.00 | PTPN1 (0.82) | PTPN1PTPN12PTPN22MAOBBCHE | |
| SCHEMBL9779522 | 0.91 | MAPT (0.84) | PTPN1PTPN12PTPN22MAOBBCHE | |
| SCHEMBL9779526 | 0.91 | MAPT (0.84) | PTPN1PTPN12PTPN22MAOBBCHE | |
| SCHEMBL9338320 | 0.90 | PTPN1 (0.76) | PTPN1PTPN12PTPN22MAOBBCHE | |
| SCHEMBL30301794 | 0.90 | PTPN1 (0.76) | PTPN1PTPN12PTPN22MAOBBCHE | |
| SCHEMBL31441210 | 0.90 | MAPT (0.86) | PTPN1PTPN12PTPN22MAOBBCHE | |
| SCHEMBL1073090 | 0.90 | MAPT (0.86) | PTPN1PTPN12PTPN22MAOBBCHE | |
| SCHEMBL1073092 | 0.90 | MAPT (0.86) | PTPN1PTPN12PTPN22MAOBBCHE | |
| SCHEMBL31441212 | 0.90 | MAPT (0.86) | PTPN1PTPN12PTPN22MAOBBCHE | |
| SCHEMBL32681391 | 0.89 | MAOB (0.72) | PTPN1PTPN12PTPN22MAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5942544-A | α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |
| US-3989708-A | HYPOTENSIVE, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |