Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | XIAP | P98170 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685032 | 1.00 | SLC7A5 (0.60) | SLC7A5ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL20899684 | 0.99 | SLC7A5 (0.58) | SLC7A5ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL20899685 | 0.99 | SLC7A5 (0.58) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL15024161 | 0.90 | MAOB (0.61) | PKMKMT2ALTA4HSMN1; SMN2MAOB | |
| SCHEMBL5116303 | 0.90 | PTPN1 (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL2039627 | 0.89 | SMN1; SMN2 (0.56) | PKMKMT2ALTA4HMEN1HSP90AA1 | |
| SCHEMBL20905989 | 0.89 | SMN1; SMN2 (0.56) | PKMKMT2ALTA4HMEN1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL29985601 | 0.87 | SMN1; SMN2 (0.55) | PKMKMT2ALTA4HMEN1HSP90AA1 | |
| SCHEMBL25359079 | 0.85 | SLC7A5 (0.56) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL25356665 | 0.85 | SLC7A5 (0.56) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995023603-A1 | USE OF 2-AMINO-4,5,7,8-TETRAHYDRO-6H-THIAZOLO[5,4-D]AZEPINES SUBSTITUTED IN POSITION 6 AS MEDICAMENTS HAVING AN ANTI-DEPRESSANT EFFECT, AND PREPARATION THEREOF | DR. KARL THOMAE GMBH (DE) | 1995-09-08 | — | — | WO | claimed |
| WO-1995023603-A1 | USE OF 2-AMINO-4,5,7,8-TETRAHYDRO-6H-THIAZOLO[5,4-D]AZEPINES SUBSTITUTED IN POSITION 6 AS MEDICAMENTS HAVING AN ANTI-DEPRESSANT EFFECT, AND PREPARATION THEREOF | DR. KARL THOMAE GMBH (DE) | 1995-09-08 | — | — | WO | disclosed |
| EP-0284632-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1988-10-05 | — | — | EP | disclosed |