Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.60 |
| ▸ | PDE4A | P27815 | 7/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.60 |
| ▸ | KDM1A | O60341 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367066 | 1.00 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DKDM1A | |
| SCHEMBL6996729 | 0.84 | KDM1A (0.72) | PDE4BPDE4APDE4CPDE4DKDM1A | |
| SCHEMBL6996727 | 0.84 | KDM1A (0.72) | PDE4BPDE4APDE4CPDE4DKDM1A | |
| SCHEMBL7092215 | 0.84 | KDM1A (0.72) | PDE4BPDE4APDE4CPDE4DKDM1A | |
| SCHEMBL7367513 | 0.82 | PDE4B (0.69) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7367510 | 0.82 | PDE4B (0.69) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7364134 | 0.82 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL9167416 | 0.81 | PDE4B (0.78) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7374911 | 0.81 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7365615 | 0.81 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027947-A1 | PHENYLCYCLOPROPANE COMPOUNDS AND THEIR USE AS cAMP AND TNF INHIBITORS | RHONE-POULENC RORER LTD. (GB) | 1994-12-08 | — | — | WO | disclosed |