Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 6/20 | 0.56 |
| ▸ | PLG | P00747 | 5/20 | 0.56 |
| ▸ | PLAT | P00750 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 11/20 | 0.37 |
| ▸ | MMP13 | P45452 | 11/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7369785 | 0.99 | PLAU (0.55) | PLAUPLGPLATF10USP2 | |
| SCHEMBL7380137 | 0.91 | PLAU (0.54) | PLAUPLGPLATF10USP2 | |
| Hydrochloric Acid SCHEMBL7368653 | 0.91 | PLAU (0.53) | PLAUPLGPLATF10USP2 | |
| SCHEMBL7367249 | 0.91 | PLAU (0.46) | PLAUPLGPLATMMP1MMP13 | |
| Hydrochloric Acid SCHEMBL7378654 | 0.90 | PLAU (0.54) | PLAUPLGPLATF10USP2 | |
| SCHEMBL7452604 | 0.85 | PLAU (0.60) | PLAUPLGPLATF10USP2 | |
| SCHEMBL6965698 | 0.80 | PLAU (0.54) | PLAUPLGPLATF10USP2 | |
| Hydrochloric Acid SCHEMBL6432636 | 0.80 | PLAU (0.53) | PLAUPLGPLATF10USP2 | |
| Hydrochloric Acid SCHEMBL7377124 | 0.79 | PLAU (0.54) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL7450214 | 0.79 | PLAU (0.47) | PLAUPLGPLATUSP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |